Hereditární nádorová onemocnění v klinické praxi – Foretová Lenka (2022)

Hereditary tumor diseases constitute a significant portion of malignant diseases. For some tumors, hereditary causes are rare, but for example, hereditary causes can be identified in up to 20% of ovarian cancer patients. There are more than 200 different tumor syndromes. Nowadays, with the development of molecular genetics, the diagnosis of tumor predisposition is important in oncology and medical genetics, as well as in many other fields of medicine. General practitioners, gynecologists, pediatricians, gastroenterologists, as well as surgeons, plastic surgeons, neurologists, dermatologists, ophthalmologists, and other specialties are also interested in testing their patients. In all these fields, it is necessary to know the possibilities of diagnostics, the risks of tumor predisposition, and the options for preventive care. The book focuses on the practical aspects of decision-making regarding genetic testing for oncology patients or their family members, on navigating the known risk factors of individual syndromes, and above all, on how to conduct preventive monitoring for high-risk individuals, where prevention is based on regular specialized check-ups as well as primary cancer prevention with the help of...