Izotretinoin v praxi – Nevoralová Zuzana (2025)

Isotretinoin belongs to the first near-aromatic generation of retinoids. Because it uniquely acts on all four main etiopathogenetic factors of acne, it is the most effective medication in treating this very unpleasant skin disease. It is primarily used for the treatment of the most severe forms of acne. However, its use is also possible for a number of other diseases, such as psoriasis, perioral dermatitis, inverse acne, and other conditions. Isotretinoin is highly effective and safe when used according to recommended guidelines. Treatment is also possible for most patients with other diseases and laboratory abnormalities. Moderate physical activities during treatment are permissible. To maintain the positive effect induced by previous therapy with oral isotretinoin, subsequent treatment with topical retinoids is very important.

However, many doctors still have concerns about treatment with oral isotretinoin, which is precisely why the book 'Isotretinoin in Practice' was written. The first edition received very positive feedback. However, since many facts have changed since 2012, a second, updated, and expanded edition is now being published. The book serves as a practical guide on how to proceed with the treatment of patients with severe forms of acne.

And this applies not only to completely healthy patients but also to...