Karcinom rekta - Od diagnózy po multidisciplinární léčbu – Ihnát Peter (2021)

The publication offers a comprehensive overview of current knowledge in evidence-based medicine. Various aspects of rectal cancer are presented – from a historical overview to the etiopathogenesis and diagnosis of the disease, individual treatment modalities with an emphasis on surgical techniques, to the issue of intestinal stomas. The focus is on problematic areas of treatment management: the role of radiotherapy in the multimodal therapy of rectal cancer, laparoscopic and robotic rectal resection, transanal total mesorectal excision, functional disorders after low rectal resection (LARS syndrome), modern treatment strategies such as 'watch and wait' or 'liver-first', perioperative care ERAS (enhanced recovery after surgery), quality of life and complications related to intestinal stomas, adequate histopathological examination of the rectal resection, etc. The monograph systematically processes the indications, benefits, and limitations of individual therapeutic modalities in the management of various stages of the disease (transanal and transabdominal resection techniques, radiotherapy, systemic treatment, locally ablative techniques). The publication identifies key factors influencing treatment outcomes and helps to understand the fundamental importance of close...