Imunologie a imunopatologie lidské reprodukce - vybrané kapitoly – Ulčová-Gallová Zdenka, Madar Jindřich (2020)

The reason for writing this publication, contributed to by our leading experts in immunology and reproductive medicine, is the growing number of evidence that improper immune function in the reproductive system is one of the key causes of fertility disorders. Today, it is estimated that 15% of couples with reduced fertility have an imbalance specifically in immunological reactions during the reproductive period. The field of reproductive immunology thus includes the diagnosis of immunologically conditioned reduced fertility, as well as methods of immunological therapy. The monograph summarizes the current knowledge about the function of immunity in relation to reproduction. It briefly describes the physiological immunological processes involved in the formation and maturation of gametes, fertilization, and embryo implantation. The main focus is then on describing individual disorders related to immunity in the area of reproduction, their diagnosis, and treatment procedures. The book is primarily intended for doctors dealing with fertility disorders, i.e., gynecologists and specialists in reproductive medicine, as well as clinical immunologists, and other professionals encountering couples suffering from reduced fertility, recurrent miscarriages, and disorders or immunological risks during pregnancy. It should assist in making thoughtful decisions regarding...